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Large-scale epigenome imputation improves data quality and disease variant enrichment

With hundreds of epigenomic maps, the opportunity arises to exploit the correlated nature of epigenetic signals, across both marks and samples, for large-scale prediction of additional datasets. Here, we undertake epigenome imputation by leveraging such correlations through an ensemble of regression...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Ernst, Jason, Kellis, Manolis
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512306/
https://ncbi.nlm.nih.gov/pubmed/25690853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3157
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