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Using a Gene Expression Biomarker to Identify DNA Damage-Inducing Agents in Microarray Profiles

High-throughput transcriptomic technologies are increasingly being used to screen environmental chemicals in vitro to provide mechanistic context for regulatory testing. The TGx-DDI biomarker is a 64-gene expression profile generated from testing 28 model chemicals or treatments (13 that cause DNA d...

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Detalhes bibliográficos
Publicado no:Environ Mol Mutagen
Main Authors: Corton, J. Christopher, Williams, Andrew, Yauk, Carole L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875442/
https://ncbi.nlm.nih.gov/pubmed/30329178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22243
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