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An enhanced machine learning tool for cis-eQTL mapping with regularization and confounder adjustments

Many expression quantitative trait loci (eQTL) studies have been conducted to investigate the biological effects of variants in gene regulation. However, these eQTL studies may suffer from low or moderate statistical power and overly conservative false-discovery rate. In practice, most algorithms fo...

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書目詳細資料
發表在:Genet Epidemiol
Main Authors: Yan, Kang K., Zhao, Hongyu, Wu, Joseph T., Pang, Herbert
格式: Artigo
語言:Inglês
出版: 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875251/
https://ncbi.nlm.nih.gov/pubmed/32700329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22341
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