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An enhanced machine learning tool for cis-eQTL mapping with regularization and confounder adjustments

Many expression quantitative trait loci (eQTL) studies have been conducted to investigate the biological effects of variants in gene regulation. However, these eQTL studies may suffer from low or moderate statistical power and overly conservative false-discovery rate. In practice, most algorithms fo...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Genet Epidemiol
Päätekijät: Yan, Kang K., Zhao, Hongyu, Wu, Joseph T., Pang, Herbert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875251/
https://ncbi.nlm.nih.gov/pubmed/32700329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22341
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