Hepatic Ago2 Regulates PPARα for Oxidative Metabolism Linked to Glycemic Control in Obesity and Post Bariatric Surgery

Argonaute 2 (Ago2) is the main component of the RNA-induced silencing complex. We recently showed that liver-specific Ago2-deficiency in mice (L-Ago2 knockout [KO] mice) enhances mitochondrial oxidation and alleviates obesity-associated pathophysiology. However, the precise mechanisms behind the rol...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Bhattacharjee, Jashdeep, Borra, Vishnupriya J, Salem, Esam S B, Zhang, Cai, Murakami, Kazutoshi, Gill, Rupinder K, Kim, Ahlee, Kim, James K, Salazar-Gonzalez, Rosa-Maria, Warren, Mikako, Kohli, Rohit, Nakamura, Takahisa
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875175/
https://ncbi.nlm.nih.gov/pubmed/33567453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqab007
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