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Expanding molecular roles of UV-DDB: shining light on genome stability and cancer
UV-damaged DNA binding protein (UV-DDB) is a heterodimeric complex, composed of DDB1 and DDB2, and is involved in global genome nucleotide excision repair. Mutations in DDB2 are associated with xeroderma pigmentosum complementation group E. UV-DDB forms a ubiquitin E3 ligase complex with cullin-4A a...
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| Veröffentlicht in: | DNA Repair (Amst) |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7873659/ https://ncbi.nlm.nih.gov/pubmed/32739133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2020.102860 |
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