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Using a sequence-specific coarse-grained model for studying protein liquid-liquid phase separation

The formation of membraneless organelles (MLOs) via liquid-liquid phase separation (LLPS) of biomolecules is a topic that has garnered significant attention in the scientific community recently. Experimental studies have revealed that intrinsically disordered proteins (IDPs) may play a major role in...

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Détails bibliographiques
Publié dans:Methods Enzymol
Auteurs principaux: Regy, Roshan M., Zheng, Wenwei, Mittal, Jeetain
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873582/
https://ncbi.nlm.nih.gov/pubmed/33453922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2020.07.009
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