ZBTB20 regulates WNT/CTNNB1 signalling pathway by suppressing PPARG during hepatocellular carcinoma tumourigenesis

BACKGROUND & AIMS: Zinc finger and BTB domain containing 20 (ZBTB20) has been implicated as a potential oncogene in liver cancer. However, knockout studies have shown it to be a transcriptional repressor of the alpha-foetoprotein (Afp) gene in adult liver, and reduced levels of ZBTB20 allow for...

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Detalhes bibliográficos
Publicado no:JHEP Rep
Main Authors: To, Jeffrey C., Chiu, Amy P., Tschida, Barbara R., Lo, Lilian H., Chiu, Cynthia H., Li, Xiao-Xiao, Kuka, Timothy P., Linden, Michael A., Amin, Khalid, Chan, Wing-Cheung, Bell, Jason B., Moriarity, Branden S., Largaespada, David A., Keng, Vincent W.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873381/
https://ncbi.nlm.nih.gov/pubmed/33604532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2020.100223
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