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Small-Conductance Ca(2+)-Activated K(+) Channels 2 in the Hypothalamic Paraventricular Nucleus Precipitates Visceral Hypersensitivity Induced by Neonatal Colorectal Distension in Rats

Visceral hypersensitivity is one of the pivotal pathophysiological features of visceral pain in irritable bowel syndrome (IBS). Small-conductance Ca(2+)-activated K(+) channel (SK) is critical for a variety of functions in the central nervous system (CNS), nonetheless, whether it is involved in the...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Ji, Ning-Ning, Du, Lei, Wang, Ying, Wu, Ke, Chen, Zi-Yang, Hua, Rong, Zhang, Yong-Mei
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873043/
https://ncbi.nlm.nih.gov/pubmed/33584280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.605618
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