Small-Conductance Ca(2+)-Activated K(+) Channels 2 in the Hypothalamic Paraventricular Nucleus Precipitates Visceral Hypersensitivity Induced by Neonatal Colorectal Distension in Rats

Visceral hypersensitivity is one of the pivotal pathophysiological features of visceral pain in irritable bowel syndrome (IBS). Small-conductance Ca(2+)-activated K(+) channel (SK) is critical for a variety of functions in the central nervous system (CNS), nonetheless, whether it is involved in the...

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Опубликовано в: :Front Pharmacol
Главные авторы: Ji, Ning-Ning, Du, Lei, Wang, Ying, Wu, Ke, Chen, Zi-Yang, Hua, Rong, Zhang, Yong-Mei
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873043/
https://ncbi.nlm.nih.gov/pubmed/33584280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.605618
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