Small-Conductance Ca(2+)-Activated K(+) Channels 2 in the Hypothalamic Paraventricular Nucleus Precipitates Visceral Hypersensitivity Induced by Neonatal Colorectal Distension in Rats

Visceral hypersensitivity is one of the pivotal pathophysiological features of visceral pain in irritable bowel syndrome (IBS). Small-conductance Ca(2+)-activated K(+) channel (SK) is critical for a variety of functions in the central nervous system (CNS), nonetheless, whether it is involved in the...

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Udgivet i:Front Pharmacol
Main Authors: Ji, Ning-Ning, Du, Lei, Wang, Ying, Wu, Ke, Chen, Zi-Yang, Hua, Rong, Zhang, Yong-Mei
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873043/
https://ncbi.nlm.nih.gov/pubmed/33584280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.605618
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