Recombinant Lactococcus lactis Carrying IL-4 and IL-10 Coding Vectors Protects against Type 1 Diabetes in NOD Mice and Attenuates Insulitis in the STZ-Induced Model

Type 1 diabetes (T1D) is an autoimmune disease that culminates in beta cell destruction in the pancreas and, subsequently, deficiency in insulin production. Cytokines play a crucial role in the development of diabetes, orchestrating the recruitment and action of immune cells, to not only destroy ins...

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Vydáno v:J Diabetes Res
Hlavní autoři: Preisser, Tatiane M., da Cunha, Vanessa P., Santana, Mariana P., Pereira, Vanessa B., Cara, Denise C., Souza, Bianca M., Miyoshi, Anderson
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872750/
https://ncbi.nlm.nih.gov/pubmed/33604389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6697319
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