Lactococcus lactis carrying the pValac eukaryotic expression vector coding for IL-4 reduces chemically-induced intestinal inflammation by increasing the levels of IL-10-producing regulatory cells

BACKGROUND: Inflammatory bowel diseases are characterized by chronic intestinal inflammation that leads to severe destruction of the intestinal mucosa. Therefore, the understanding of their aetiology as well as the development of new medicines is an important step for the treatment of such diseases....

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Veröffentlicht in:Microb Cell Fact
Hauptverfasser: Souza, Bianca Mendes, Preisser, Tatiane Melo, Pereira, Vanessa Bastos, Zurita-Turk, Meritxell, de Castro, Camila Prósperi, da Cunha, Vanessa Pecini, de Oliveira, Rafael Pires, Gomes-Santos, Ana Cristina, de Faria, Ana Maria Caetano, Machado, Denise Carmona Cara, Chatel, Jean-Marc, Azevedo, Vasco Ariston de Carvalho, Langella, Philippe, Miyoshi, Anderson
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006358/
https://ncbi.nlm.nih.gov/pubmed/27576902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0548-x
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