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Mycobacterial Hsp65 antigen delivered by invasive Lactococcus lactis reduces intestinal inflammation and fibrosis in TNBS-induced chronic colitis model

Intestinal fibrosis associated with Crohn’s disease (CD), which a common and serious complication of inflammatory bowel diseases. In this context, heat shock proteins (HSPs) might serve as an alternative treatment because these antigens play important roles in the regulation of effector T cells. We...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: da Cunha, Vanessa Pecini, Preisser, Tatiane Melo, Santana, Mariana Passos, Machado, Denise Carmona Cara, Pereira, Vanessa Bastos, Miyoshi, Anderson
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674425/
https://ncbi.nlm.nih.gov/pubmed/33208841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77276-8
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