Mycobacterial Hsp65 antigen delivered by invasive Lactococcus lactis reduces intestinal inflammation and fibrosis in TNBS-induced chronic colitis model

Intestinal fibrosis associated with Crohn’s disease (CD), which a common and serious complication of inflammatory bowel diseases. In this context, heat shock proteins (HSPs) might serve as an alternative treatment because these antigens play important roles in the regulation of effector T cells. We...

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Bibliographic Details
Published in:	Sci Rep
Main Authors:	da Cunha, Vanessa Pecini, Preisser, Tatiane Melo, Santana, Mariana Passos, Machado, Denise Carmona Cara, Pereira, Vanessa Bastos, Miyoshi, Anderson
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group UK 2020
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7674425/ https://ncbi.nlm.nih.gov/pubmed/33208841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77276-8
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Mycobacterial Hsp65 antigen delivered by invasive Lactococcus lactis reduces intestinal inflammation and fibrosis in TNBS-induced chronic colitis model

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