Immune evasive human islet-like organoids ameliorate diabetes

While stem cell-derived islets hold promise as a therapy for insulin-dependent diabetes, challenges remain in achieving this goal(1–6). Here we generate human islet-like organoids (HILOs) from induced pluripotent stem cells (iPSCs) and show that non-canonical WNT4 signaling drives the metabolic matu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nature
Main Authors: Yoshihara, Eiji, O’Connor, Carolyn, Gasser, Emanuel, Wei, Zong, Oh, Tae Gyu, Tseng, Tiffany W., Wang, Dan, Cayabyab, Fritz, Dai, Yang, Yu, Ruth T., Liddle, Christopher, Atkins, Annette R., Downes, Michael, Evans, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872080/
https://ncbi.nlm.nih.gov/pubmed/32814902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2631-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados