טוען...

A-to-I RNA editing of Alu dsRNAs is markedly decreased in MS; unedited Alu dsRNAs but not edited Alu dsRNAs are potent activators of pro-inflammatory transcriptional responses

Sensors that detect double stranded RNA stimulate IFN-responses as a defense against viral infection. IFN-responses are also well documented in a variety of human autoimmune diseases including relapsing remitting multiple sclerosis in which increased IFN-responses result from increased levels of dou...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Immunol
Main Authors: Tossberg, John T., Heinrich, Rachel M., Farley, Virginia M., Crooke, Philip S., Aune, Thomas M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872017/
https://ncbi.nlm.nih.gov/pubmed/33046502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000384
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!