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A-to-I RNA editing of Alu dsRNAs is markedly decreased in MS; unedited Alu dsRNAs but not edited Alu dsRNAs are potent activators of pro-inflammatory transcriptional responses
Sensors that detect double stranded RNA stimulate IFN-responses as a defense against viral infection. IFN-responses are also well documented in a variety of human autoimmune diseases including relapsing remitting multiple sclerosis in which increased IFN-responses result from increased levels of dou...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Immunol |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7872017/ https://ncbi.nlm.nih.gov/pubmed/33046502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000384 |
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