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Reduced A-to-I editing of endogenous Alu RNAs in severe COVID-19 disease
Severe COVID-19 disease is associated with elevated inflammatory responses. One form of Aicardi-Goutières Syndrome caused by inactivating mutations in ADAR results in reduced A-to-I editing of endogenous double-stranded RNAs (dsRNAs), induction of IFNs, interferon-stimulated genes (ISGs), other infl...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8183577/ https://ncbi.nlm.nih.gov/pubmed/33782089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2001428 |
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