Metformin attenuates plaque-associated tau pathology and reduces amyloid-β burden in APP/PS1 mice

BACKGROUND: The neuropathological hallmarks of Alzheimer’s disease (AD) are amyloid-β (Aβ) plaques and neurofibrillary tangles (NFTs). The amyloid cascade theory is the leading hypothesis of AD pathology. Aβ deposition precedes the aggregation of tau pathology and Aβ pathology precipitates tau patho...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Alzheimers Res Ther
Autors principals: Chen, Yanxing, Zhao, Shuai, Fan, Ziqi, Li, Zheyu, Zhu, Yueli, Shen, Ting, Li, Kaicheng, Yan, Yaping, Tian, Jun, Liu, Zhirong, Zhang, Baorong
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7871393/
https://ncbi.nlm.nih.gov/pubmed/33563332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00761-9
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars