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Mutational processes in cancer preferentially affect binding of particular transcription factors

Protein binding microarrays provide comprehensive information about the DNA binding specificities of transcription factors (TFs), and can be used to quantitatively predict the effects of DNA sequence variation on TF binding. There has also been substantial progress in dissecting the patterns of muta...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Mo, Boot, Arnoud, Ng, Alvin W. T., Gordân, Raluca, Rozen, Steven G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870974/
https://ncbi.nlm.nih.gov/pubmed/33558557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82910-0
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