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Stability selection for regression-based models of transcription factor–DNA binding specificity

Motivation: The DNA binding specificity of a transcription factor (TF) is typically represented using a position weight matrix model, which implicitly assumes that individual bases in a TF binding site contribute independently to the binding affinity, an assumption that does not always hold. For thi...

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Detalhes bibliográficos
Main Authors: Mordelet, Fantine, Horton, John, Hartemink, Alexander J., Engelhardt, Barbara E., Gordân, Raluca
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694650/
https://ncbi.nlm.nih.gov/pubmed/23812975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt221
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