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Stability selection for regression-based models of transcription factor–DNA binding specificity
Motivation: The DNA binding specificity of a transcription factor (TF) is typically represented using a position weight matrix model, which implicitly assumes that individual bases in a TF binding site contribute independently to the binding affinity, an assumption that does not always hold. For thi...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694650/ https://ncbi.nlm.nih.gov/pubmed/23812975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt221 |
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