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QBiC-Pred: quantitative predictions of transcription factor binding changes due to sequence variants

Non-coding genetic variants/mutations can play functional roles in the cell by disrupting regulatory interactions between transcription factors (TFs) and their genomic target sites. For most human TFs, a myriad of DNA-binding models are available and could be used to predict the effects of DNA mutat...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Martin, Vincentius, Zhao, Jingkang, Afek, Ariel, Mielko, Zachery, Gordân, Raluca
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602471/
https://ncbi.nlm.nih.gov/pubmed/31114870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz363
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