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Neuropeptide Y (NPY) intranasal delivery alleviates Machado–Joseph disease

Machado–Joseph disease (MJD) is the most common dominantly-inherited ataxia worldwide with no effective treatment to prevent, stop or alleviate its progression. Neuropeptide Y (NPY) is a neuroprotective agent widely expressed in the mammalian brain. Our previous work showed that NPY overexpression m...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Duarte-Neves, Joana, Cavadas, Cláudia, Pereira de Almeida, Luís
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870889/
https://ncbi.nlm.nih.gov/pubmed/33558582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82339-5
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