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Cross-linking mass spectrometry uncovers protein interactions and functional assemblies in synaptic vesicle membranes

Synaptic vesicles are storage organelles for neurotransmitters. They pass through a trafficking cycle and fuse with the pre-synaptic membrane when an action potential arrives at the nerve terminal. While molecular components and biophysical parameters of synaptic vesicles have been determined, our k...

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Foilsithe in:Nat Commun
Main Authors: Wittig, Sabine, Ganzella, Marcelo, Barth, Marie, Kostmann, Susann, Riedel, Dietmar, Pérez-Lara, Ángel, Jahn, Reinhard, Schmidt, Carla
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870876/
https://ncbi.nlm.nih.gov/pubmed/33558502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21102-w
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