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Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

Proteins interact with their ligands to form active and dynamic assemblies which carry out various cellular functions. Elucidating these interactions is therefore fundamental for the understanding of cellular processes. However, many protein complexes are dynamic assemblies and are not accessible by...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Vis Exp
Prif Awduron: Haupt, Caroline, Hofmann, Tommy, Wittig, Sabine, Kostmann, Susann, Politis, Argyris, Schmidt, Carla
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MyJove Corporation 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755487/
https://ncbi.nlm.nih.gov/pubmed/29286378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56747
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