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Synaptic Vesicles Are Constitutively Active Fusion Machines, Which Function Independently of Ca(2+)

BACKGROUND: In neurones, release of neurotransmitter occurs through the fusion of synaptic vesicles with the plasma membrane. Many proteins required for this process have been identified, with the SNAREs syntaxin 1, SNAP-25 and synaptobrevin thought to constitute the core fusion machinery. However,...

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Detalhes bibliográficos
Main Authors: Holt, Matthew, Riedel, Dietmar, Stein, Alexander, Schuette, Christina, Jahn, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481520/
https://ncbi.nlm.nih.gov/pubmed/18485705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.04.069
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