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Synaptic Vesicles Are Constitutively Active Fusion Machines, Which Function Independently of Ca(2+)

BACKGROUND: In neurones, release of neurotransmitter occurs through the fusion of synaptic vesicles with the plasma membrane. Many proteins required for this process have been identified, with the SNAREs syntaxin 1, SNAP-25 and synaptobrevin thought to constitute the core fusion machinery. However,...

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Main Authors: Holt, Matthew, Riedel, Dietmar, Stein, Alexander, Schuette, Christina, Jahn, Reinhard
格式: Artigo
語言:Inglês
出版: 2008
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481520/
https://ncbi.nlm.nih.gov/pubmed/18485705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.04.069
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