Targeting autophagy enhances atezolizumab-induced mitochondria-related apoptosis in osteosarcoma

In this study, we identified the multifaceted effects of atezolizumab, a specific monoclonal antibody against PD-L1, in tumor suppression except for restoring antitumor immunity, and investigated the promising ways to improve its efficacy. Atezolizumab could inhibit the proliferation and induce immu...

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Pubblicato in:Cell Death Dis
Autori principali: Liu, Zhuochao, Wang, Hongyi, Hu, Chuanzhen, Wu, Chuanlong, Wang, Jun, Hu, Fangqiong, Fu, Yucheng, Wen, Junxiang, Zhang, Weibin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870858/
https://ncbi.nlm.nih.gov/pubmed/33558476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03449-6
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