Genome-Scale CRISPR-Cas9 Transcriptional Activation Screening in Metformin Resistance Related Gene of Prostate Cancer

Metformin is a classic type II diabetes drug which possesses anti-tumor properties for various cancers. However, different cancers do not respond to metformin with the same effectiveness or acquire resistance. Thus, searching for vulnerabilities of metformin-resistant prostate cancer is a promising...

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Bibliografski detalji
Izdano u:Front Cell Dev Biol
Glavni autori: Chen, Jiahong, Huang, Yaqiang, Tang, Zhenfeng, Li, Maozhang, Ling, Xiaohui, Liao, Jinxian, Zhou, Xiaobo, Fang, Shumin, Zhao, Haibo, Zhong, Weide, Yuan, Xia
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Cell and Developmental Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870801/
https://ncbi.nlm.nih.gov/pubmed/33575255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.616332
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