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Gnas Inactivation Alters Subcutaneous Tissues in Progression to Heterotopic Ossification

Heterotopic ossification (HO), the formation of bone outside of the skeleton, occurs in response to severe trauma and in rare genetic diseases such as progressive osseous heteroplasia (POH). In POH, which is caused by inactivation of GNAS, a gene that encodes the alpha stimulatory subunit of G prote...

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Publicado en:Front Genet
Autores principales: Brewer, Niambi, Fong, John T., Zhang, Deyu, Ramaswamy, Girish, Shore, Eileen M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870717/
https://ncbi.nlm.nih.gov/pubmed/33574833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.633206
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