Experimental Trypanosoma cruzi Infection Induces Pain in Mice Dependent on Early Spinal Cord Glial Cells and NFκB Activation and Cytokine Production

The neglected tropical infirmity Chagas disease (CD) presents high mortality. Its etiological agent T. cruzi is transmitted by infected hematophagous insects. Symptoms of the acute phase of the infection include fever, fatigue, body aches, and headache, making diagnosis difficult as they are present...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Borghi, Sergio M., Fattori, Victor, Carvalho, Thacyana T., Tatakihara, Vera L. H., Zaninelli, Tiago H., Pinho-Ribeiro, Felipe A., Ferraz, Camila R., Staurengo-Ferrari, Larissa, Casagrande, Rubia, Pavanelli, Wander R., Cunha, Fernando Q., Cunha, Thiago M., Pinge-Filho, Phileno, Verri, Waldiceu A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870690/
https://ncbi.nlm.nih.gov/pubmed/33574810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.539086
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