Metabolic syndrome agravates cardiovascular, oxidative and inflammatory dysfunction during the acute phase of Trypanosoma cruzi infection in mice

We evaluated the influence of metabolic syndrome (MS) on acute Trypanosoma cruzi infection. Obese Swiss mice, 70 days of age, were subjected to intraperitoneal infection with 5 × 10(2) trypomastigotes of the Y strain. Cardiovascular, oxidative, inflammatory, and metabolic parameters were evaluated i...

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izdano v:Sci Rep
Main Authors: Lucchetti, Bruno Fernando Cruz, Boaretto, Natalia, Lopes, Fernanda Novi Cortegoso, Malvezi, Aparecida Donizette, Lovo-Martins, Maria Isabel, Tatakihara, Vera Lúcia Hideko, Fattori, Victor, Pereira, Rito Santo, Verri, Waldiceu Aparecido, de Almeida Araujo, Eduardo Jose, Pinge-Filho, Phileno, Martins-Pinge, Marli Cardoso
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906468/
https://ncbi.nlm.nih.gov/pubmed/31827186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55363-9
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