Experimental Trypanosoma cruzi Infection Induces Pain in Mice Dependent on Early Spinal Cord Glial Cells and NFκB Activation and Cytokine Production

The neglected tropical infirmity Chagas disease (CD) presents high mortality. Its etiological agent T. cruzi is transmitted by infected hematophagous insects. Symptoms of the acute phase of the infection include fever, fatigue, body aches, and headache, making diagnosis difficult as they are present...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Borghi, Sergio M., Fattori, Victor, Carvalho, Thacyana T., Tatakihara, Vera L. H., Zaninelli, Tiago H., Pinho-Ribeiro, Felipe A., Ferraz, Camila R., Staurengo-Ferrari, Larissa, Casagrande, Rubia, Pavanelli, Wander R., Cunha, Fernando Q., Cunha, Thiago M., Pinge-Filho, Phileno, Verri, Waldiceu A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870690/
https://ncbi.nlm.nih.gov/pubmed/33574810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.539086
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