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Dysregulation of endocytic machinery and ACE2 in small airways of smokers and COPD patients can augment their susceptibility to SARS-CoV-2 (COVID-19) infections

Lungs of smokers and chronic obstructive pulmonary disease (COPD) are severely compromised and are susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) attack. The dangerous combination of enhanced SARS-CoV-2 attachment receptor protein ACE2 along with an increase in endocytic...

詳細記述

保存先:
書誌詳細
出版年:Am J Physiol Lung Cell Mol Physiol
主要な著者: Eapen, Mathew Suji, Lu, Wenying, Hackett, Tillie L., Singhera, Gurpreet Kaur, Thompson, Isobel E., McAlinden, Kielan Darcy, Hardikar, Ashutosh, Weber, Heinrich C., Haug, Greg, Wark, Peter A. B., Chia, Collin, Sohal, Sukhwinder Singh
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7869956/
https://ncbi.nlm.nih.gov/pubmed/33174446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00437.2020
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