Dysregulation of endocytic machinery and ACE2 in small airways of smokers and COPD patients can augment their susceptibility to SARS-CoV-2 (COVID-19) infections

Lungs of smokers and chronic obstructive pulmonary disease (COPD) are severely compromised and are susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) attack. The dangerous combination of enhanced SARS-CoV-2 attachment receptor protein ACE2 along with an increase in endocytic...

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Bibliografski detalji
Izdano u:Am J Physiol Lung Cell Mol Physiol
Glavni autori: Eapen, Mathew Suji, Lu, Wenying, Hackett, Tillie L., Singhera, Gurpreet Kaur, Thompson, Isobel E., McAlinden, Kielan Darcy, Hardikar, Ashutosh, Weber, Heinrich C., Haug, Greg, Wark, Peter A. B., Chia, Collin, Sohal, Sukhwinder Singh
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2021
Teme:
Rapid Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7869956/
https://ncbi.nlm.nih.gov/pubmed/33174446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00437.2020
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