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HGF Airway Over-expression Leads to Enhanced Pulmonary Vascularization without Induction of VEGF

The hepatocyte growth factor (HGF)/c-Met signaling pathway mediates angiogenesis. We have previously reported that airway expression of a human HGF transgene (HGF TG) produced mice that were more susceptible to lung tumorigenesis induced by 4-(methylnitrosoamino)-1-(3-pyridyl)-1-butanone (NNK). Here...

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Detalhes bibliográficos
Publicado no:Curr Angiogenes
Main Authors: Henry, Cassandra, Lopez-Chavez, Ariel, Stabile, Laura P., Siegfried, Jill M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7869858/
https://ncbi.nlm.nih.gov/pubmed/33564620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2211552811201010052
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