Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies

The evolution of SARS-CoV-2 could impair recognition of the virus by human antibody-mediated immunity. To facilitate prospective surveillance for such evolution, we map how convalescent plasma antibodies are impacted by all mutations to the spike’s receptor-binding domain (RBD), the main target of p...

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Bibliographic Details
Published in:Cell Host Microbe
Main Authors: Greaney, Allison J., Loes, Andrea N., Crawford, Katharine H.D., Starr, Tyler N., Malone, Keara D., Chu, Helen Y., Bloom, Jesse D.
Format: Artigo
Language:Inglês
Published: Elsevier Inc. 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7869748/
https://ncbi.nlm.nih.gov/pubmed/33592168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2021.02.003
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