Modulation of hypochlorous acid (HOCl) induced damage to vascular smooth muscle cells by thiocyanate and selenium analogues

The production of hypochlorous acid (HOCl) by myeloperoxidase (MPO) plays a key role in immune defense, but also induces host tissue damage, particularly in chronic inflammatory pathologies, including atherosclerosis. This has sparked interest in the development of therapeutic approaches that decrea...

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Veröffentlicht in:Redox Biol
Hauptverfasser: Flouda, Konstantina, Gammelgaard, Bente, Davies, Michael J., Hawkins, Clare L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7868818/
https://ncbi.nlm.nih.gov/pubmed/33550113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101873
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