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Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages

Myeloperoxidase (MPO) is a vital component of the innate immune system, which produces the potent oxidant hypochlorous acid (HOCl) to kill invading pathogens. However, an overproduction of HOCl during chronic inflammatory conditions causes damage to host cells, which promotes disease, including athe...

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Pubblicato in:Redox Biol
Autori principali: Guo, Chaorui, Davies, Michael J., Hawkins, Clare L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417949/
https://ncbi.nlm.nih.gov/pubmed/32781424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101666
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