Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages

Myeloperoxidase (MPO) is a vital component of the innate immune system, which produces the potent oxidant hypochlorous acid (HOCl) to kill invading pathogens. However, an overproduction of HOCl during chronic inflammatory conditions causes damage to host cells, which promotes disease, including athe...

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Veröffentlicht in:Redox Biol
Hauptverfasser: Guo, Chaorui, Davies, Michael J., Hawkins, Clare L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417949/
https://ncbi.nlm.nih.gov/pubmed/32781424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101666
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