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The role of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) in the induction of mitochondrial dysfunction in macrophages
A host of chronic inflammatory diseases are accelerated by the formation of the powerful oxidant hypochlorous acid (HOCl) by myeloperoxidase (MPO). In the presence of thiocyanate (SCN(-)), the production of HOCl by MPO is decreased in favour of the formation of a milder oxidant, hypothiocyanous acid...
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| Publicado no: | Redox Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7315103/ https://ncbi.nlm.nih.gov/pubmed/32570189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101602 |
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