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Inhibition of vascular smooth muscle cell calcification by ATP analogues

Arterial medial calcification (AMC) has been associated with phenotypic changes in vascular smooth muscle cells (VSMCs) that reportedly makes them more osteoblast-like. Previous work has shown that ATP/UTP can inhibit AMC directly via P2 receptors and indirectly by NPP1-mediated hydrolysis to produc...

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Detalles Bibliográficos
Publicado en:Purinergic Signal
Main Authors: Patel, Jessal J., Bourne, Lucie E., Millán, José Luis, Arnett, Timothy R., MacRae, Vicky E., Wheeler-Jones, Caroline P. D., Orriss, Isabel R.
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737162/
https://ncbi.nlm.nih.gov/pubmed/31338672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-019-09672-3
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