CDCA8, targeted by MYBL2, promotes malignant progression and olaparib insensitivity in ovarian cancer

Ovarian cancer is the most lethal gynecologic malignancy. Poly (ADP-ribose) polymerase inhibitors (PARPi) are effective in treating ovarian cancer. However, cancer cell insensitivity and resistance remain challenges. Determination of the exact chemoresistance mechanisms and potential targeted therap...

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Bibliografiske detaljer
Udgivet i:Am J Cancer Res
Main Authors: Qi, Gonghua, Zhang, Chenyi, Ma, Hanlin, Li, Yingwei, Peng, Jiali, Chen, Jingying, Kong, Beihua
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2021
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7868764/
https://ncbi.nlm.nih.gov/pubmed/33575078
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