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Olaparib in the management of ovarian cancer
Alterations in the homologous repair pathway are thought to occur in 30%–50% of epithelial ovarian cancers. Cells deficient in homologous recombination rely on alternative pathways for DNA repair in order to survive, thereby providing a potential target for therapy. Olaparib, a poly(ADP-ribose) poly...
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| Publicado no: | Pharmgenomics Pers Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538690/ https://ncbi.nlm.nih.gov/pubmed/26309417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S62809 |
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