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Profile of olaparib in the treatment of advanced ovarian cancer

Olaparib is a poly(ADP-ribose) polymerase inhibitor that received accelerated approval from the US Food and Drug Administration as monotherapy for patients with germline BRCA mutations and ovarian cancer treated with three or more prior lines of chemotherapy. This article summarizes the mechanism of...

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Detalhes bibliográficos
Publicado no:Int J Womens Health
Main Authors: Chase, Dana M, Patel, Shreya, Shields, Kristin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847603/
https://ncbi.nlm.nih.gov/pubmed/27186080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJWH.S55906
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