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Synthesis, Characterization, Cellular Uptake, and In Vitro Anticancer Activity of Fullerenol-Doxorubicin Conjugates

Doxorubicin (DOX) is one of the most commonly used chemotherapeutic agents for treating human cancer. However, its clinical use has been limited by DOX-induced cardiotoxicity as well as other side effects. In the present study, we designed and synthesized the fullerenol (FU)-DOX conjugates and folic...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Xu, Beihua, Yuan, Li, Hu, Ying, Xu, Zhiyuan, Qin, Jiang-Jiang, Cheng, Xiang-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7868567/
https://ncbi.nlm.nih.gov/pubmed/33568999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.598155
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