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Effect simultaneous delivery with P-glycoprotein inhibitor and nanoparticle administration of doxorubicin on cellular uptake and in vitro anticancer activity

Multidrug resistance (MDR) is the most common problem of inadequate therapeutic response in tumor cells. Many trials has been developed to overcome drug efflux by P-glycoprotein (P-gp). For instance, co-administration of a number of drugs called chemosensitizers or MDR modulators with a chemotherape...

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Detalhes bibliográficos
Publicado no:Saudi Pharm J
Main Authors: Esim, Ozgur, Sarper, Meral, Ozkan, Cansel K., Oren, Sema, Baykal, Baris, Savaser, Ayhan, Ozkan, Yalcin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7132609/
https://ncbi.nlm.nih.gov/pubmed/32273806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2020.02.008
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