The Protein Secretome Is Altered in Rectal Cancer Tissue Compared to Normal Rectal Tissue, and Alterations in the Secretome Induce Enhanced Innate Immune Responses

SIMPLE SUMMARY: Rectal cancer occurs in the lower part of the bowel, and approximately half of all rectal cancer patients receive chemoradiotherapy before surgery. In ~22% of cases the tumour is eradicated, but the reasons for different response rates between patients are largely unknown. Inflammati...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Heeran, Aisling B., Dunne, Margaret R., Morrissey, Maria E., Buckley, Croí E., Clarke, Niamh, Cannon, Aoife, Donlon, Noel E., Nugent, Timothy S., Durand, Michael, Dunne, Cara, Larkin, John O., Mehigan, Brian, McCormick, Paul, Lynam-Lennon, Niamh, O’Sullivan, Jacintha
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7867296/
https://ncbi.nlm.nih.gov/pubmed/33540635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13030571
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