Radiation-induced Bystander Effect (RIBE) alters mitochondrial metabolism using a human rectal cancer ex vivo explant model

Locally advanced rectal cancer is treated with neoadjuvant-chemoradiotherapy, however only 22% of patients achieve a complete response. Resistance mechanisms are poorly understood. Radiation-induced Bystander Effect (RIBE) describes the effect of radiation on neighbouring unirradiated cells. We inve...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Heeran, Aisling B., Berrigan, Helen P., Buckley, Croí E., Bottu, Heleena Moni, Prendiville, Orla, Buckley, Amy M., Clarke, Niamh, Donlon, Noel E., Nugent, Timothy S., Durand, Michael, Dunne, Cara, Larkin, John O., Mehigan, Brian, McCormick, Paul, Brennan, Lorraine, Lynam-Lennon, Niamh, O'Sullivan, Jacintha
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586242/
https://ncbi.nlm.nih.gov/pubmed/33129115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100882
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