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Advances and Obstacles in Homology-Mediated Gene Editing of Hematopoietic Stem Cells
Homology-directed gene editing of hematopoietic stem and progenitor cells (HSPCs) is a promising strategy for the treatment of inherited blood disorders, obviating many of the limitations associated with viral vector-mediated gene therapies. The use of CRISPR/Cas9 or other programmable nucleases and...
Uloženo v:
| Vydáno v: | J Clin Med |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7867106/ https://ncbi.nlm.nih.gov/pubmed/33535527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10030513 |
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