In Vitro and In Vivo Antitumor Activity of Indolo[2,3-b] Quinolines, Natural Product Analogs from Neocryptolepine Alkaloid

Neocryptolepine (5-methyl-5H-indolo[2,3-b] quinoline) analogs were synthesized and evaluated in vitro and in vivo for their effect versus Ehrlich ascites carcinoma (EAC). The analogs showed stronger cytotoxic activity against EAC cells than the reference drug. The in vivo evaluation of the target co...

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Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: Altwaijry, Najla, El-Ghlban, Samah, El Sayed, Ibrahim E.-T., El-Bahnsawye, Mohamed, Bayomi, Asmaa I., Samaka, Rehab M., Shaban, Elkhabiry, Elmongy, Elshaymaa I., El-Masry, Thanaa A., Ahmed, Hytham M. A., Attallah, Nashwah G. M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7867085/
https://ncbi.nlm.nih.gov/pubmed/33535575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26030754
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