In Vitro and In Vivo Antitumor Activity of Indolo[2,3-b] Quinolines, Natural Product Analogs from Neocryptolepine Alkaloid

Neocryptolepine (5-methyl-5H-indolo[2,3-b] quinoline) analogs were synthesized and evaluated in vitro and in vivo for their effect versus Ehrlich ascites carcinoma (EAC). The analogs showed stronger cytotoxic activity against EAC cells than the reference drug. The in vivo evaluation of the target co...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Molecules
मुख्य लेखकों: Altwaijry, Najla, El-Ghlban, Samah, El Sayed, Ibrahim E.-T., El-Bahnsawye, Mohamed, Bayomi, Asmaa I., Samaka, Rehab M., Shaban, Elkhabiry, Elmongy, Elshaymaa I., El-Masry, Thanaa A., Ahmed, Hytham M. A., Attallah, Nashwah G. M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2021
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7867085/
https://ncbi.nlm.nih.gov/pubmed/33535575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26030754
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